Studies on 1-Azabicyclo Compounds. (4). : Synthesis of 4-Substituted Octahydroisoquinolizines

Synthesis and characterization of some novel linear azo-azomethine compounds based on 1-bromo, 4-4-4-nitrophenylazo phenoxy butane

The reaction of some carbocyclic and heterocyclic Schiff bases with the synthesized 1-bromo, 4-[4-(4-nitrophenylazo) phenoxy] butane and formation of novel linear azo-azomethine compounds in good to excellent yields were investigated. The compounds were fully characterized by UV-Vis, FT-IR, 1H NMR spectroscopic techniques and elemental analysis. Effects of various solvents on their visible abso...

Synthesis, Characterization and Study of Some N-Substituted Aryl-2- ({4-[(Substituted Aryl Carbamoyl) Methyl]-5-(Pyridin-4-yl)-4H-1, 2, 4-Triazol-3-yl} Sulfanyl) Acetamide

Pathogenic infections and inflammation are very common ailments humans suffer. Upsurge of resistant pathogens has impeded the antimicrobial drug development process in recent years and the search of new antimicrobial agents is clearly evident from the literature. In line with these developments the synthesis of N-substituted aryl-2-({4-[(substituted aryl carbamoyl) methyl]-5-(pyridin-4-yl)-4H-1...

synthesis and docking studies of novel antifungals based on 4-substituted imidazole

Studies on inclusion complexes of 2-[Substituted arylideamino]-1, 3, 4-thiadiazino [6,5b]indole with β- Cyclodextrin

Inclusion complexes of 2-[Arylidenamino]-1,3,4-thiadiazino[6,5b]indoles have been prepared with β-cyclodextrin so as to increase the solubility of these compounds in polar medium which may increase theirbioaccessibility. The formation of inclusion complexes is known from the study of changes in physical andspectral properties of the compounds. The stability of the inclusion complexes has been s...

Synthesis of Some Novel Thiazolidin-4-one Substituted 1, 2,4 - Triazoles of Their Antimicrobial Activity Studies

Thiazolidine-4-one substituted 1, 2, 4triazole and benzofuran heterocyclic have received considerable attention during last two decades as they are endowed with variety of biological activities and have wide range of therapeutic properties. A literature survey indicates that benzofuran derivatives possess different pharmacological and biological activities, of which the most potent is anti-micr...